Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0001p075 | (1) | WCRB2014

Chromatin remodelling gene Cecr2 in murine gametogenesis, fertilization, and early embryonic development

Norton Kacie A , McDermid Heather E

Mammalian reproduction is dependent on a myriad of genes, all of which must be carefully regulated spatially and temporally to ensure successful fertilization and embryonic development. Chromatin remodellers are able to affect nuclear processes such as gene transcription, DNA replication, recombination and repair through modulation of chromatin structure. Mice with hypomorphic mutations in the chromatin remodelling gene Cecr2 have normal reproductive histology and the...